Hansel Laboratory Department of Pathology

Hansel Lab Team

 

Donna Hansel, MD, PhD

Donna Hansel received her MD PHD from the Johns Hopkins School of Medicine in 2001. She completed her residency and fellowship at the Johns Hopkins Hospital and is board-certified in Anatomic Pathology. She is nationally recognized as a leader in urologic pathology and serves on a number of bladder cancer advisory boards. Her research focuses in the mechanism of mTOR activity in promoting bladder cancer growth and invasion.

   

Andrew Hau, PhD

Andrew Hau received his undergraduate degree in Biochemistry and Molecular & Cellular Biology at the University of Arizona (2006) and went to Oregon State University for his Ph.D. in Pharmacy (2012). During his graduate studies, Dr. Hau focused on elucidating the mechanism of action of coibamide A, a novel anti-cancer compound produced by a Panamanian cyanobacterium, and was involved in other marine drug discovery efforts. He is particularly interested in continuing his training in cancer biology by investigating mTOR signaling dysregulation in cancer and how this pathway regulates downstream processes such as autophagy, cell growth and proliferation, and motility.

 

Divya Sahu, PhD

Divya Sahu received her undergraduate engineering degree in Biotechnology, from Birla Institute of Technology – Mesra in India, and was awarded the University Gold Medal. She subsequently pursued her PhD from University of Southern California. In her doctoral thesis, she discovered the critical functional element F-5, within the Heat Shock Protein 90alpha which is responsible for its novel pro-motility role in breast cancer and wound healing. She also developed a monoclonal antibody against F-5 currently being pursued as a potential anti-cancer therapeutic. She is continuing her interest in cancer cell motility in her postdoctoral research in the Hansel lab, studying the role of arginine – nitric oxide metabolic pathway in bladder cancer invasion and progression and its cross-talk with other key pathways, including the mTOR pathway.

       

Former Lab Members

 

Sounak Gupta, MBBS, PhD
Lab: 2010-2013

Sounak Gupta received his medical degree (MBBS.) from Kasturba Medical College, India, following which he pursued a doctorate in Molecular Medicine in the laboratory of Dr. Doug Cavener at the Pennsylvania State University. Sounak completed his postdoctoral fellowship in the Hansel lab, where he defined the role of mTORC2 in driving bladder cancer invasion and upstream regulation of mTORC2 by TGF-B. Sounak is currently a molecular and urologic pathology fellow at MSKCC and has accepted a faculty position at the Mayo Clinic.

 

 

Kazufumi Nakashima, MD
Lab: 2015-2016

Kazufumi Nakashima received his MD from School of Medicine at Nihon University in Japan (2006). He began his medical internship in the School of Medicine at Kanazawa University (2008-2011), where he worked under Professor Mikio Namiki. Kazufumi was also actively involved in research on human papilloma virus with Dr. Kazuyoshi Shigehara. Kazufumi specializes in urology at Kanazawa University. Kazufumi was a visiting scholar in the Hansel lab and focused his research on unique target identification downstream from mTORC2.

 

Goutam Krish
Lab: 2013-2015

Goutam Krish is an undergraduate from the University of California- San
Diego who graduated in 2015 with a degree in Human Biology. His research focused on predicting the effects of mTOR inhibitors on bladder cancer cell survival through - OMIC approaches. Goutam is currently a student at SPEA Dental at UCSF.

 

 

Manando Nakasaki, MD
Lab: 2015-2017

Manando Nakasaki received his MD from Osaka University, Japan following which he pursued residency training in Orthopedic Surgery. He then received his PhD from Osaka University, where his research focused primarily on the mechanisms of osteoblast migration. While he was in the Hansel lab, he studied the expression profile of mTOR signaling components in bladder cancer and determining factors of urethral stricture recurrence. Manando is now pursuing pathology residency training at UC Irvine.

 

Mariah Zampieri Leivo, MD
Lab: 2014-2016

Mariah received her MD from the Federal School of Medicine and Surgery in Rio de Janeiro, Brazil. During her studies, she focused on identifying diagnostic methods in anatomic pathology, prioritizing patient care. One of her notable research projects validated a new strategy for diagnosing pulmonary tuberculosis, which she helped implement into her medical school’s teaching hospital. Mariah relocated to the U.S., where she continued her training in the Hansel lab with a focus on translational research and molecular pathology in the context of invasive bladder cancer. Her research focused on the development of novel diagnostic and prognostic markers in urothelial carcinoma. She is currently a resident in Pathology at UC San Diego.

       

 

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