Hansel Laboratory Department of Pathology

Hansel Lab Team

 

Donna Hansel, MD, PhD

Donna Hansel received her MD PHD from the Johns Hopkins School of Medicine in 2001, with her laboratory research focused on pro-motility factors in olfactory neurons. She completed her residency and fellowship at the Johns Hopkins Hospital and is board-certified in Anatomic Pathology. She is nationally recognized as a leader in urologic pathology and serves on a number of bladder cancer advisory boards. Her research interest is to identify novel therapeutic strategies for patients with advanced bladder cancer, including strategies to target cell migration and metastatic spread in this disease.

   

Andrew Hau, PhD

Andrew Hau received his undergraduate degree in Biochemistry and Molecular & Cellular Biology at the University of Arizona (2006) and went on to Oregon State University for his Ph.D. in Pharmacy (2012). During his graduate studies, Dr. Hau focused on elucidating the mechanism of action of coibamide A, a novel anti-cancer compound produced by a Panamanian cyanobacterium, and was involved in other marine drug discovery efforts. He is particularly interested in continuing his training in cancer biology by investigating mTOR signaling dysregulation in cancer and how pathway regulates downstream processes such as autophagy, cell growth and proliferation, and motility.

 

Divya Sahu, PhD

Divya Sahu received her undergraduate engineering degree in Biotechnology, from Birla Institute of Technology – Mesra in India, and was awarded the University Gold Medal. She went on to pursue her PhD from University of Southern California. In her doctoral thesis, she discovered the critical functional element F-5, within the Heat Shock Protein 90alpha which is responsible for its novel pro-motility role in breast cancer and wound healing. She also developed a monoclonal antibody against F-5 currently being pursued as a potential anti-cancer therapeutic. She is continuing her interest in cancer cell motility during her postdoctoral research in the Hansel lab, studying the role of Arginine – Nitric Oxide metabolic pathway in bladder cancer invasion and progression and its cross-talk with other key pathways.

 

 

Mariah Zampieri Leivo, MD

Mariah received her MD from the Federal School of Medicine and Surgery in Rio de Janeiro, Brazil.  During her studies, she focused on identifying diagnostic methods in anatomic pathology, prioritizing patient care.  One of her notable research projects validated a new strategy for diagnosing pulmonary tuberculosis, which she helped implement into her medical school’s teaching hospital.  Mariah relocated to the U.S., where she continues her training and career with a focus on translational research and molecular pathology in the context of invasive bladder cancer.  At the Hansel laboratory, she is investigating new therapeutic approaches for bladder cancer by studying the downstream targets of mTORC2 complex and the microenvironment of urothelial neoplasia.  Mariah is fluent in English and Portuguese, and conversational in Spanish.

 

Goutam Krish

Goutam Krish is an undergraduate from the University of California- San
Diego who will be graduating in 2015 with a degree in Human Biology. He
joined the lab in the summer of 2013 and has been studying the role of
mTOR in bladder cancer. He is currently investigating how mTOR inhibitor
drugs affect cell invasion and proliferation in bladder cancer.

       

Former Lab Members

 

Sounak Gupta, MBBS, PhD

Sounak Gupta has been a post-doctoral fellow in my lab since the fall of 2010. Sounak received his medical degree (MBBS.) from Kasturba Medical College, India, following which he pursued a doctorate in Molecular Medicine in the laboratory of Dr. Doug Cavener at the Pennsylvania State University. Sounak has primarily been studying the role of mTOR signaling in the progression of bladder cancer.

 

 

Kazufumi Nakashima, MD

Kazufumi Nakashima received his MD from School of Medicine at Nihon University in Japan (2006). He began his medical internship in the School of Medicine at Kanazawa University (2008-2011), where he worked under Professor Mikio Namiki. Kazufumi was also actively involved in research on Human Papilloma Virus with Dr. Kazuyoshi Shigehara. Kazufumi specializes in urological operations at Kanazawa University. He is currently interested in continuing his research training in bladder cancer as a Visiting Scholar at UCSD.

 

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