Hansel Laboratory Department of Pathology

mTOR signaling and its role in bladder cancer progression

Dr. Donna Hansel

  • A major focus of my laboratory is investigation of mammalian target of rapamycin (mTOR) signaling in bladder cancer progression. We have recently focused on the effects of mTORC2 in migration and invasion, including upstream and downstream effectors. A major focus of my laboratory is the use of translational approaches, such as human bladder cancer ex vivo models and human cancer specimens, to identify novel mTOR-related processes in this disease. In addition to my laboratory work, I am also Chief of the Division of Anatomic Pathology at UC San Diego.
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About the Lab


Our research lab is located in the Biomedical Sciences Building on the UC San Diego La Jolla campus location. We use live cell imaging techniques, cell signaling assays, mouse xenograft models, and ex vivo human models to identify mTOR-driven pro-motility functions in bladder cancer... More about our research >

Research Opportunities

The lab welcomes undergraduates, graduate students and postdoctoral fellows who have an interest and/or experience in cancer biology and cancer cell migration.

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